The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives.
نویسندگان
چکیده
Using evolved pyrrolysyl-tRNA synthetase-tRNA(CUA)(Pyl) pairs, L-phenylalanine, p-iodo-L-phenylalanine and p-bromo-L-phenylalanine have been genetically incorporated into proteins at amber mutation sites in E. coli.
منابع مشابه
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ورودعنوان ژورنال:
- Molecular bioSystems
دوره 7 3 شماره
صفحات -
تاریخ انتشار 2011